Lobular Carcinoma In Situ

Lobular Carcinoma In Situ

Lobular Carcinoma In Situ(LCIS)

When there is an increased growth of abnormal cells in the lobules of the breast it is called lobular carcinoma in situ (LCIS). This condition as the name suggests is not a cancerous (malignant) growth but it puts an individual on a higher risk of developing invasive breast cancer. This growth starts in the milk producing glands of the breast and is limited to the lobules. This condition usually affects more than on lobule of the breast. men are rarely known t have been diagnosed with this condition and it affects women primarily before menopause at the age group of 40 to 50. As this not a malignant condition, it is also referred to as “lobular neoplasia” where neoplasia is a collection of abnormal cells.

Symptoms of Lobular Carcinoma In Situ

LCIS is not always presented with any visible symptoms to the breast or a lump or firming of tissue. It may also not be detected on a mammogram as there is no micro-calcification in the cancer cells. Cancer cells usually have small calcium specks which is referred to as micro-calcification and shows up on mammogram. Sometimes this condition is never diagnosed in absence of symptoms and any harmful effect.

Diagnosis and Tests Required for Lobular Carcinoma In Situ

LCIS is not a direct deduction of any investigation aimed at finding LCIS due to bsence of visible symptoms. But this condition is diagnosed when a breast investigation due to any other reason is being done. It may start with an abnormal mammogram or in some cases due to a lump in the breast. this is usually followed by a biopsy which gives a conclusive result of the condition and diagnoses the LCIS condition. The biopsy procedure can vary as per the initial finding:

  • Fine needle aspiration Biopsy: very small hole is made which leaves no scar and through it by inserting a very small, hollow needle sample of cells is removed from the breast which is then examined by the pathologist under the microscope.
  • Core needle biopsy: cases which requires a slightly larger tissue sample, with the help of a comparatively larger needle is used to withdraw tissue from the breast. a tiny incision is made in this process which leaves small scar.
  • Incisional biopsy: Incisional biopsy is a small surgical process in which a small piece of tissue is removed for examination.
  • Excisional biopsy: Incisional biopsy is a small surgical process in the entire lump of suspicions and abnormal tissue is removed for examination.

LCIS is difficult to diagnose as it may appear like the DCIS on examination by the pathologist under the microscope. DCIS is a malignant tumor growth as compared to LCIS which is a benign cell growth. DCIS warrants cancer treatment intervention to prevent damage unlike LCIS which causes no damage. LCIS in predominant cases affects both the breasts and can be found in multiple sites in the breast.

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